Many people take fish oil supplements to try to improve various aspects of their health, but new work from the Cleveland Clinic has suggested that high doses of an omega-3 fatty acid supplement don't help people at high risk of…
Read More High Dose Fish Oil Does Not Reduce Risk of Cardiac Events
Klinefelter syndrome (KS) is a sex chromosome variation caused by the presence of one or more supernumerary X chromosomes. Common clinical phenotypes of KS are comprised of tall stature with a feminine body type, gynecomastia, small testes and infertility. Cases…
Read More Recognition of Genital Differences Among Some 47XXY Infants
Klinefelter syndrome (KS) is the most common sex-chromosome variation among males, with an estimated prevalence of 1:660 newborns. The most common karyotype is the classic 47,XXY, which accounts for the 80–90% of all cases. It is a consequence of a…
Read More Evidence For Long Noncoding RNA Up-regulation in Klinefelter Syndrome
The X chromosome and X-linked variants have largely been ignored in genome-wide and candidate association studies of infectious diseases due to the complexity of statistical analysis of the X chromosome. This exclusion is significant, since the X chromosome contains a…
Read More The X Chromosome: Sex-specific Effects in Infectious Disease
The XXY community mourns the passing of Fred Diener an XXY trailblazer of San Diego, California, who died on the 23rd of October, aged sixty-five years. Long before KS&A (AXYS) Fred was a pioneer for the XXY community running a…
In the remaining three cases, there was no mention of TRT. We were unable to find a case where TRT was re-initiated in a patient with KS post cancer treatment, as was our patient’s wish
The Vienna Declaration states that human rights are universal, indivisible, interdependent and interrelated. The VDPA makes clear that “every person is born equal and has the same rights to life and welfare, education and work, living independently and active participation…
Read More U.N Human Rights Council to Investigate Violations and Abuses Against Intersex Persons.
Mayfield, who is intersex, was born 47XXY, meaning she has one additional sex chromosome. This left Mayfield neither completely biologically male nor female, but both. Raised male by her parents, Mayfield transitioned to female after having to be placed on estrogen due to health problems and to save her life.
For those in the community who find themselves piling on weight with or without of exogenous sex hormones, could this be a more probably cause? Scientists have discovered that depressed individuals show higher levels of inflammation as well as elevated…
Read More Depression Causes Inflammation and Metabolic Imbalances
A Rare Breed tells the story of Rob Wilson a Tasmanian Chicken and Pig breeder who also happens to be XXY. Rob was born with two complete sets of male and female gonads and was operated on as a child…
