BACKGROUND Dyspnoea and syncope are common causes of admission to hospitals. Pulmonary embolism is often a differential diagnosis, and by examining the clinical history the clinician searches for known predisposing factors. This case report highlights the importance of Klinefelter’s syndrome…
Read More Pulmonary Embolism in a Patient with Klinefelter’s Syndrome
Many people take fish oil supplements to try to improve various aspects of their health, but new work from the Cleveland Clinic has suggested that high doses of an omega-3 fatty acid supplement don't help people at high risk of…
Read More High Dose Fish Oil Does Not Reduce Risk of Cardiac Events
Klinefelter syndrome (KS) is the most common sex-chromosome variation among males, with an estimated prevalence of 1:660 newborns. The most common karyotype is the classic 47,XXY, which accounts for the 80–90% of all cases. It is a consequence of a…
Read More Evidence For Long Noncoding RNA Up-regulation in Klinefelter Syndrome
The Centres for Disease Control and Prevention (CDC) estimates that in 2018, obesity impacted about 42 percent of American adults. People with obesity are at higher risk for many diseases, including type 2 diabetes, coronary heart disease, and stroke; they also tend to generally…
The tendency towards thromboembolism is a serious complication related to Klinefelter's Syndrome. Some KS patients may suffer from VTE in the form of deep vein thrombosis or pulmonary embolism, or both while others may complain of recurrent venous ulcers. The primary cause of this increased risk of VTE in KS patients is not clearly understood and so this has encouraged scientists to look for the cause and whether it is an outcome of an underlying genetic susceptibility, hormonal disturbances, or both.
It's been hypothesised that XXY's are biological females dressed in male clothing, that being so we ask you keep in mind when reading how an XXY experience might have greater similarity to females than males, of course none of this…
Read More The Promises and Pitfalls of Sex Difference Research
Is clinical prescription of testosterone therapy associated with short-term risk of venous thromboembolism in men with and without hypogonadism? In this case-crossover study comparing 6-month testosterone use for 39,622 men who had a venous thromboembolism with testosterone use 6 to…
Klinefelter’s syndrome: Associations with increased blood clot (thrombosis)events (deep venous thrombosis, pulmonary embolus, venousthromboembolism). Free consultation and evaluation. The close association of Klinefelter’s syndrome (47XXY) with unexplained thrombosis has been known for at least 33 years. Venous thromboemboli (VTE) are…
Given the high incidence of Sleep Apnoea amongst XXY's administering exogenous Testosterone, research of this nature would seem to indicate a far greater impact than insomnia alone. Most people have at some point echoed Macbeth’s complaint about the loss of…
